A Model Sex/Health Education Curriculum for Middle-Level Students in Taiwan

The purpose of this project was to develop a model sex/health education curriculum for middle-level students in Taiwan. To accomplish the purpose, a review of related literature was conducted. Additionally, related information/materials from selected sources was obtained and analyzed

VBF vs. GGF Higgs with Full-Event Deep Learning: Towards a Decay-Agnostic Tagger

We study the benefits of jet- and event-level deep learning methods in distinguishing vector boson fusion (VBF) from gluon-gluon fusion (GGF) Higgs production at the LHC. We show that a variety of classifiers (CNNs, attention-based networks) trained on the complete low-level inputs of the full event achieve significant performance gains over shallow machine learning methods (BDTs) trained on jet kinematics and jet shapes, and we elucidate the reasons for these performance gains. Finally, we take initial steps towards the possibility of a VBF vs. GGF tagger that is agnostic to the Higgs decay mode, by demonstrating that the performance of our event-level CNN does not change when the Higgs decay products are removed. These results highlight the potentially powerful benefits of event-level deep learning at the LHC.Comment: 21 pages+appendices, 16 figures; added references, updated Pythia shower scheme for VBF, and added Appendix C for version

Regulation of axon repulsion by MAX-1 SUMOylation and AP-3.

During neural development, growing axons express specific surface receptors in response to various environmental guidance cues. These axon guidance receptors are regulated through intracellular trafficking and degradation to enable navigating axons to reach their targets. In Caenorhabditis elegans, the UNC-5 receptor is necessary for dorsal migration of developing motor axons. We previously found that MAX-1 is required for UNC-5-mediated axon repulsion, but its mechanism of action remained unclear. Here, we demonstrate that UNC-5-mediated axon repulsion in C. elegans motor axons requires both max-1 SUMOylation and the AP-3 complex β subunit gene, apb-3 Genetic interaction studies show that max-1 is SUMOylated by gei-17/PIAS1 and acts upstream of apb-3 Biochemical analysis suggests that constitutive interaction of MAX-1 and UNC-5 receptor is weakened by MAX-1 SUMOylation and by the presence of APB-3, a competitive interactor with UNC-5. Overexpression of APB-3 reroutes the trafficking of UNC-5 receptor into the lysosome for protein degradation. In vivo fluorescence recovery after photobleaching experiments shows that MAX-1 SUMOylation and APB-3 are required for proper trafficking of UNC-5 receptor in the axon. Our results demonstrate that SUMOylation of MAX-1 plays an important role in regulating AP-3-mediated trafficking and degradation of UNC-5 receptors during axon guidance

Prevalence of Dyslipidemia in Patients Receiving Health Checkups: A Hospital-Based Study

We used the dataset from one medical center in Taiwan to explore the prevalence of dyslipidemia, which included 2695 subjects receiving private health checkups in 2003-2004. The overall prevalence of hypercholesterolemia was 53.3% in men and 48.2% in women (P = 0.008). The overall prevalence of hypertriglyceridemia was 29.3% in men and 13.7% in women (P < 0.001). The overall prevalence of elevated LDL level was 50.7% in men and 37.9% in women (P < 0.001). The overall prevalence of low HDL level was 47.4% in men and 53% in women (P = 0.004)